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Relative to daily injections of the GLP-1R mono-agonist control liraglutide (1.8 mg), both MEDI0382 dosages at 100 g and 200 g decrease body weight to an approximately equal degree over the course of 54 weeks

British Journal of Experimental Pathology

ApoE represents a significant risk factor for VD, with meta-analyses demonstrating heightened susceptibility to VD in individuals with the ApoE4 allele compared to those with the ApoE3 allele (Yin et al., 2012)