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Ratain MJ, Nakamura Y, Cox NJ

T2DM Increases Risk of MASLD Development and Progression In a recent meta-analysis of 123 observational cohort studies involving about 2.22 million individuals with T2DM, Younossi et al

By the Monday after that, about 0.25 mg remains

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Until Wegovys MASH indication, patients with F2F3 fibrosis lacked any FDAapproved pharmacologic therapy targeting steatohepatitis resolution and fibrosis improvement, relying primarily on lifestyle modification and bariatric surgery. Against this background, semaglutides ability to deliver sustained doubledigit percentage weight loss, improve cardiometabolic markers, reduce MACE, and favorably modify histologic endpoints in MASH positions Wegovy as a versatile agent across cardiometabolic care pathways, provided its risks and limitations are fully understood and respected