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[2] Traditional oral agents remain important options: Metformin continues as first-line therapy for most patients, though it can cause gastrointestinal symptoms initially

Aptamers, also known as chemical antibodies, are single-stranded oligonucleotides that shape a three-dimensional structure and bind to their targets just like antibodies [210]

Signal Transduct Target Ther 9(1):234 Meloni AR et al (2013) GLP-1 receptor activated insulin secretion from pancreatic -cells: mechanism and glucose dependence

A 1015 minute brisk walk after meals is enough to make a real difference

Metabolism of purine bases, nucleosides and alkaloids in theobromine-forming Theobroma cacao leaves