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Lipid rafts (or cholesterol-rich nanodomains) are regions within the plasma membrane where weak binding between cholesterol and other phospholipids allows specific protein interactions to occur (Saxena and Chattopadhyay, 2012), as well as for effective serotonin control of food intake and prevention of hyperphagia (van Galen et al., 2021)

2024;6:ojae069

this may be of particular concern in older patients who often experience a natural decline in renal function with age and may be more susceptible to the effects of dehydration

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49 The semaglutide development process shows that the lipidation approach is decisive to the selectivity of the protein