GHK-Cu shifts expression of 4,000+ genes toward younger phenotypes upregulating DNA repair, collagen synthesis, and antioxidant pathways while suppressing inflammatory mediators
It may be that these types of cancer are less sensitive to IGF-1, or that they are able to produce this hormone themselves locally. Dr Knuppel says
This outcome is thought to be an effect of all medications that increase GLP-1, because of both an increase in SDF-1-alpha and capillary density due to increased hypoxia-inducible factor 1-alpha and vascular endothelial growth factor
Dysregulation of copper ions can disturb lipid metabolism, resulting in oxidative stress, mitochondrial damage and endothelial cell dysfunction (14), and induce atherosclerosis and other cardiovascular diseases such as arrhythmia and cardiomyopathy (15)
Said ER, Nagui NAER, Rashed LA, Mostafa WZ