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The expanding use of immune checkpoint inhibitors (ICIs) in cancer therapy has been associated with a higher incidence of immune-related adverse events (irAEs) ( Fluoroquinolones (e.g., moxifloxacin) have been associated with DILI as well as SJS/TEN, and in the context of ICI therapy these agents may amplify immune-mediated toxicities ( vs type B), offering a pragmatic framework for phenotype-aware monitoring and risk stratification
However, this profile appears to differ for tirzepatide interactions with mouse incretin receptors
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