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The finding raises the question of whether the risk of hepatotoxicity from statins is higher for men or if it more reflective of sex differences in statin prescription rates, being higher in men than in women, as has been previously identified in studies evaluating patients with conditions ranging from heart failure to HCV and HIV

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Results An EGCGzinc (EGCGZn) nanocomplex was prepared via metalpolyphenol coordination and formulated into a thermosensitive rectal suppository for localized delivery

Patients received placebo, low-dose (50 mg/kg/day), or high-dose (200 mg/kg/day) vitamin C every 6 hours for 4 days