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Grandin, T

Beyond the masculinizing effects, steroid use can lead to significant hormonal disruption, acne, mood swings, liver strain, and an increased risk of cardiovascular problems

Nitric oxide inhibition of tobacco catalase and ascorbate peroxidase

Screening of a variety of solvents (including MeOH, DMSO, THF, MeCN, EA) indicated that 1,4-dioxane was the best solvent (93% NMR yield and 90% isolated yield of the desired product, Supplementary Table 1, entries 813)

Developer strategy : Both are Novo Nordisk programs, suggesting the company views them as complementary rather than competing -- CagriSema as the nearer-term injectable option, amycretin as the longer-term oral strategy