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Methods In this study, we recruited a cohort comprising children with obesity (body mass index over two z -scores above the age/sex-adjusted mean of the Spanish reference population, age range: 612 years), born to parents with obesity ( N = 18) or without obesity ( N = 41), as well as matched healthy controls ( N = 26)

All experiments were performed in GLP-1R HEK293 cells and with the exception of panel G (n=3), all panels show the mean + S.E.M of 5 independent experiments performed in duplicate or triplicate

Tolkien, The Hobbit Gastric emptying is now appreciated to be central to the pathophysiology and rational management of diabetes (type 1, type 2 and pancreatogenic)

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