glp 1 synthesis GLP-1 and Its Role in Glycogen Production: A Narrative Review GIP and GLP-1: similarities and

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This insulin resistance affects the liver directly, promoting increased de novo lipogenesis and endogenous glucose production, thereby driving both hepatic steatosis and hyperglycemia

The slowed gastric emptying from GLP-1 therapy could theoretically exacerbate inflammation or obstruction risk in active Crohn's, though controlled clinical data specific to this population remains limited