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25 The dosing schedule was 1000 g daily for 7 days, then 1000 g once per week for 1 month, then 1 1000 g injection monthly for 6 months

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However, there are also some host factors, such as polymorphism of the IL-1, which influences gastric acid secretion, or polymorphism of the CYP2C19, which is the main enzyme metabolizing PPI (proton pump inhibitor), that are associated with the risk of gastric cancer development (Uotani et al

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