Data obtained in photostability testing should be used to apply proper handling, packaging, and labeling of a drug substance and predict its possible side effects (connected with light exposure) and drug delivery system (e.g., it should be applied to infusion solutions which are often stored in transparent bottlesthe consequence is long exposure of drug substance on indoor light) (Tonnesen 2004
Food and Drug Administration (FDA) approved Eli Lilly and Company's Zepbound (tirzepatide) injection, the first and only obesity treatment that activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors
Newer data presented at ENDO 2024 surprisingly suggests that GLP-1s may reduce the recurrence of acute pancreatitis compared with some other diabetes drugs in certain high-risk groups
While this study possesses several strengthsincluding its prospective design, strict inclusion criteria, and well-matched control groupit is also subject to certain limitations that should be considered when interpreting the results
These agents benefit individuals with atherosclerosis, heart failure, or chronic kidney disease (CKD) (6)