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Cells were lysed by ultrasonication (Sonic Dismembrator Model 500, Fisher Scientific), and the lysate was clarified by centrifugation (35,000 g, 30 min)

VRK2 expression stratifies the response of PC to GSH-targeted treatment To further investigate the differential sensitivity to GSH inhibitors between VRK2-expressing and VRK2-deficient pancreatic tumors in vivo, we developed orthotopic pancreatic cancer models using Pan02 cells (Fig

In contrast, absence seizures occur more frequently upon pharmacological inhibition of cerebellar nuclei activity [105]

J Res Pharm Pract

Sterile & Non-Pyrogenic:Provides maximum safety in clinical settings