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Elashoff (79) also suggested that, compared with other common hypoglycemic drugs, GLP-1RA may increase the risk of chronic pancreatitis and then change the levels of cellular inflammatory factors and reactive oxygen species, thus increasing the risk of pancreatic cancer

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The American Heart Association recommends about 25g of fiber per day for women, and 38g per day for men

Other side effects include diarrhoea (up to 30% on semaglutide and 20% on tirzepatide), vomiting (25% vs 12% respectively), constant sinusistis/pharyngitis (up to 20%), headaches (15% vs 6%), abdominal pain (10% vs 5%)