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This method bypasses the digestive system, making it ideal for people who: Have trouble absorbing B12 due to gastrointestinal issues (like Crohns disease or coeliac disease) Are on medications that interfere with B12 absorption (like metformin or anti-acids) Follow vegan or vegetarian diets Have undergone gastric surgery

However, this is a minor factor compared to temperature, light, and solvent choice

Five mechanistic axes are documented: 1

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This is an important function, especially for individuals who get most of their iron from plant-based foods ( One study found that participants iron absorption increased by 67% when they took 100 mg of vitamin C with a meal ( However, individuals who have conditions that increase the risk of iron accumulation in the body, such as hemochromatosis, should be cautious with vitamin C supplements