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GHK-Cu stimulates collagen I, III, and elastin synthesis in fibroblasts Promotes decorin and glycosaminoglycan production for matrix integrity Attracts immune cells and promotes wound debridement and repair GHK-Cu may prevent oxidative stress in skin by regulating copper and modifying expression of numerous antioxidant genes2012Gene Expression Gene expression analysis reveals GHK-Cu upregulates antioxidant genes and downregulates pro-inflammatory genes, suggesting a protective role against oxidative stress and UV damage in skin

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doi: 10.1007/s10620-006-9738-4 253 KaurGSinghSKKumarRKumarBKumariYGulatiMet al

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