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doi: 10.1038/ijo.2009.2 62 SantiniFBusettoLCresciBSbracciaP

Pigments such as Echinochrome A attenuate immune cell infiltration, downregulate pro-inflammatory cytokines, and promote M2 macrophage polarization in murine colitis models, indicative of potential efficacy in mucocutaneous HSV lesions [144]

This report evaluates what the company states, what ingredient-level research supports under controlled study conditions, and where gaps remain between marketing language and product-level clinical evidence