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Four other patients started the study but withdrew and returned to the standard weekly dosing schedule after gaining some weight before their first three-month follow-up visit for the trial

Semaglutide ameliorates metabolism and hepatic outcomes in an NAFLD mouse model

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388 To confirm the role of GLP-1 in enhancing physical endurance and the possible mechanisms involved, an in vivo AAV-mediated GLP-1 overexpression model and an in vitro siRNA-mediated AMPK knockdown model were generated