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Diabetes Metab Syndr Obes (2019) 12:1918

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This slowed gastric emptying can trigger loose stools as your body adjusts to the medication's effects on appetite control and blood sugar regulation

Some patients find that switching to oral semaglutide, tirzepatide injections, or PlexusDx's GLP-Squared formulation produces fewer GI side effects due to different absorption kinetics or receptor activation profiles