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Under resting conditions, C/EBP suppresses the transcriptional activity of the CBP/p300-interacting trans activator with ED-rich tail 4 (CITED4) gene by directly binding to its promoter region or by recruiting transcriptional repressors such as histone deacetylases (HDACs) (181)

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By influencing these neurotransmitters, peptide DSIP can promote slow-wave sleep, regulate sleep-wake cycles, and modulate stress responses