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Supporting these are Niacinamide (3%) for barrier strengthening, Ectoin (2%) for stress protection, Beta-Glucan for anti-inflammatory support, LMW Hyaluronic Acid for deep hydration, and Betaine for moisture balance

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Study design concerns The most critical issue is that neither study was blinded

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"The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men" (PDF)