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Supplementary Table 4 (download XLSX Strain list

When shedding does occur, it is most often linked to rapid weight loss, nutritional deficiencies, or temporary stress on the body

Pharmacol Rev (2003) 55(1):16794

The six most common causes of GLP-1 fatigue are: Eating too few calories Low protein intake and muscle loss Dehydration and low electrolytes Metabolic adaptation and energy conservation Blood sugar fluctuations Poor sleep quality (often compounded by under-eating) Cause 1: Eating Too Few Calories This is the most common driver of fatigue in GLP-1 users

There is no accumulation of lisdexamfetamine and dextroamphetamine at steady state in healthy adults