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Delayed gastric emptying leaves food and liquid in the stomach longer, increasing stretch and chemical stimulus to visceral afferents that communicate with the brainstem nausea centers

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Gastroparesis can be a complication of diabetes that is related to long-standing or poorly controlled disease, the agency added, further complicating the ability to determine what role the drugs played in the reported events. For its part, Ozempic and Wegovy creator Novo Nordisk defended its buzzy drugs to CNN , noting that abdominal changes are to be expected

Of course, healthcare providers may consider prescribing off-label medication if they believe its the best fit for a patient and their health goals