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Furthermore, our modeling analyses suggest that 25HC, like fractalkine and sPLA2-IIA, interacts with v3 integrin via site-II in the extracellular domain of the 3 integrin subunit 35,36

Theyre distributed throughout the body, including in cardiac tissue

In the early 2000s, a surge of companies began exploring the potential of constrained peptides, motivated by the belief that these molecules could target previously inaccessible intracellular sites

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