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This nanoagent was self-assembled by photosensitizer Ce6 for 1 O 2 production and Fe 3+ for GSH consumption, encapsulated with polyvinylpyrrolidone (PVP) polymer, named Mn 3 [Fe(CN) 6 ] 2 -Ce 6 nanoagent (Glud-MFo-c)

Glucose (1.5 g/kg) was administered to conscious mice fasted for 6 hours ( n = 914 for each point)

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