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Additional complications involve hormone replacement in Hashimotos thyroiditis, which usually involves the administration of levothyroxine

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According to American Gastroenterological Association guidelines, osmotic laxatives like polyethylene glycol (PEG 3350) are recommended as first-line treatment for tirzepatide-induced constipation, as they are generally safe for regular use and effectively draw water into the colon to soften stools

The final decision will come from the FDA in the form of a rule proposal

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