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Summary Bottom line: Early human studies suggest GLP-1 drugs (e.g., semaglutide/Ozempic/Wegovy and tirzepatide/Mounjaro/Zepbound) can reduce alcohol cravings and sometimes heavy drinkingbut none are FDA-approved for Alcohol Use Disorder (AUD) yet

For direct cellular hypertrophy, IGF-1 LR3 remains the most studied and mechanistically potent option

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