These toxic metals disrupt thyroid function, deplete essential minerals like zinc and selenium, generate oxidative stress, and can directly damage hair follicle cells
Similarly, activating the Nrf2/HO-1 axis to enhance cellular antioxidant gene expression can hamper ferroptosis, although the potentially excessive iron release from high HO-1 expression must be considered (128)
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Mean concentrations for all medium-chain acylcarnitines [hexanoyl-L-carnitine (C6), octanoyl-L-carnitine (C8), decanoyl-L-carnitine (C10) and dodecanoyl-L-carnitine (C12)] in these cohorts were higher than in the uninfected control group
No meaningful differences were observed between sex-specific estimates, providing no evidence of effect modification by sex ( Supplementary Figures 2 , 3 )