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It is the target for several FDA-approved antidiabetic medications called incretin mimetics: These incretin mimetics are glucagon-like peptide 1 (GLP-1) analogs that mimic the physiological action of GLP-1 and thereby potentiates the incretin effect in type 2 diabetic patients

Given these reported outcomes regarding weight reduction and appetite control in obesity associated with the MC4R pathway, it is plausible to hypothesize that setmelanotide may exert similar effects in MC4R-deficient obesity

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" With Foundayo, we now have an oral option that delivered an average of 12.4% weight loss at the highest dose in clinical trials addressing both the clinical realities of obesity and the practical challenges patients face every day