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The high throughput screening campaign of the substance library provided several hit compounds one of those the drug-like aryl sulfonamide 40 that was subsequently optimized into 41 that is a metabolically stable and reversible IRAP inhibitor

Glutamate neurotransmission has important effects on synaptic activity associated with normal nervous system development, learning, and memory formation

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Ces rsultats suggrent un rle potentiel de la L-carnitine dans lamlioration de la cellulite, mais leur porte reste limite par le faible nombre de participantes et la prsence dautres actifs connus pour leur action lipolytique