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Are these improvements simply the result of weight loss, or do GLP-1 medications have direct anti-inflammatory and neuromodulatory effects

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1 If hospitalization occurs due to exacerbation or if a patient experiences two or more exacerbations with or without hospitalization, the individual falls into GOLD group E and should be treated with combination therapy of an inhaled long-acting beta-2 agonist (LABA) with a long-acting antimuscarinic (LAMA)

Update: This kept getting worse and using a smaller needle didn't help, so I'm going to switch to once-weekly injections and also dilute the drug with significantly less reconstitution solution (20 mg / mL)