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14,15 Because of the results of these landmark clinical trials, evidence-based treatment guidelines now recommend the GLP-1/GIP agonists as an important second-line treatment for uncomplicated type 2 diabetics who fail to meet hemoglobin A1c targets on popular first-line agents such as metformin

These are fundamentally different molecules with different receptor profiles

The goal is to raise the dosage gradually to help reduce the possibility of experiencing negative side effects

Tanyalcin T, Taskiran D, Topalak O, et al