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Finasteride protects dermal papilla cells by blocking the conversion of testosterone to DHT, removing the hormonal signal that triggers DPC shrinkage in androgenetic alopecia

Enhanced IL-8 expression production of both normal human keratinocytes and HaCaT cells was observed after stimulation in vitro by both irritants, sensitizer and tolerogen

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Synergy is inferred from the individual mechanisms, not demonstrated in combination: GHK-Cu: Cosmetically Focused Clinical Data Split-face human dermatology trials on wrinkle depth and skin density (n usually under 50 per arm) Microarray gene mapping (4,000+ genes)