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In the Golgi apparatus, TMEM165 (Potelle et al., 2016) and SPCA1 (Leitch et al., 2011

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First, it acted as a competitive inhibitor of 2-oxoglutarate-dependent dioxygenase (2-OGDD) function, and secondly, glutarate accumulation impaired activity of the pyruvate dehydrogenase complex (PDHc)

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doi: 10.1016/j.jclepro.2023.136452 43 Sai-UtSKingwascharapongPMazumderMARRawdkuenS