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With positive health and lifestyle interventions, patients can enjoy their weight loss for years to come

Small-molecule covalent modification of conserved cysteine leads to allosteric inhibition of the TEAD Yap protein-protein interaction

Long-Term Safety Concerns: While short-term data are promising, the long-term impact of GLP-1, dual, and triple agonists on adolescent metabolic health remains unclear

Given the scoping nature of the review and the heterogeneity of available evidence, study selection focused on identifying representative and clinically informative literature rather than exhaustive quantitative inclusion

however, several ancestry-specific signals were markedly attenuated when combining populations, likely reflecting heterogeneity in allele frequencies and LD patterns