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Optimizing Your Thyroid Hormones Before Starting Semaglutide Before beginning any GLP-1 medication, patients with Hashimoto's should ensure that thyroid stimulating hormone (TSH) and free T4 levels are in optimal rangenot just within the 'normal' laboratory reference interval

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Read Day 6 here: To view or add a comment, sign in More Relevant Posts Taking GLP-1 medication

Stress, poor sleep, and hormonal imbalances (thyroid dysfunction, cortisol dysregulation) also blunt medication efficacy

That placebo effect is fairly typical, by the way, and often happens in trials: it's thought to be a combination of the psychological boost of thinking you're being treated, plus a tendency to live more healthily and carefully if you know you're part of a study