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Even though only limited information is available regarding the regulation of GSTP1 by miRNAs, we believe that further investigations could contribute to the development of new therapeutic miRNA-based anticancer strategies

Interestingly, the increases in MEK1/2 and p70S6K1 phosphorylation were also observed when cells were subjected to the treatment of AKT inhibitor or genetic knockdown of AKT2 but not AKT1, suggesting that AKT2 inhibition stimulates MEK1/2 phosphorylation to activate p70S6K1

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doi: 10.1128/mSystems.00665-20 132 PontoizeauCGaboritCTualNSimon-SolaMRotaruIBenoistMet al

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