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Large amounts of alcohol irritate the mucosal linings in the stomach and intestines leading to a condition called gastritis which further leads to reduced absorption of B12 levels in the body

Healthy cells, which do not have elevated FOXO4-p53 complexes, are left unharmed

Nonmelanoma skin cancer happens when certain abnormal skin cells grow too quickly in the top layer of your skin (the epidermis)

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This shows that hypertension leads to iron overload in the brain, and iron overload increases OS and lipid peroxidation, thereby causing ferroptosis (Yang et al., 2020) in neurons and ultimately leading to brain injury (Figure 2)