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Sample size The sample size was estimated and computed using the computer program G*Power 3.1.9.7 (RRID: SCR 013726)

Outline known safety data and tolerability of GHK-Cu in humans Clinical reports note mild local reactions for topical application and rare systemic adverse events at low doses

Evidence suggests that an imbalance between tonic and phasic dopamine signaling, characterized by reduced baseline activity but exaggerated transient reward responses, leads to abnormally strong reward reinforcement effects and manifests clinically as impulsivity and distractibility (144)

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10.1523/JNEUROSCI.1749-20.2020 J