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Context of Use: Why the GLP-1 Revolution Exposes the Limits of In Silico Replacement Why the question is not "animal or alternative" but "what does each model actually measure?" Stefano Gaburro, PhD The Wrong Question Dominates the Debate The pharmaceutical industry is infatuated with GLP-1 receptor agonists

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Glucagon-like peptide-1 receptor agonists (GLP-1RAs)have emerged as a promising class of antidiabetic agents with potential cardiovascular benefits 3

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