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While serious liver complications from GLP-1 receptor agonists and dual GIP/GLP-1 receptor agonists are uncommon, patients and healthcare providers should remain alert to potential warning signs that warrant medical evaluation

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The highest risk appears to be in patients with type 2 diabetes who have established diabetic retinopathy at the time of treatment initiation, particularly when aggressive glycemic targets are pursued rapidly without appropriate ophthalmologic monitoring

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