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Abstract The two major deficits in type 2 diabetes, insulin resistance and impaired beta cell function, are often treated with metformin and incretin-based drugs, respectively

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Do not use GLP-1 + GIP treatments if: Warnings and Precautions: Pregnancy and Reproductive Health: GLP-1 + GIP medications may cause harm to a fetus and should not be used during pregnancy or by individuals planning to become pregnant

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Nature Reviews

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Endocrinology 151 , 46784687 (2010)

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