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The popularity of these medications created a surge in demand, which led to shortages of some GLP-1 receptor agonists that began in 2022

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Curr Med Chem 2003;10:24712483.ArticlePubMedPMC 87

In the Step 1 trial (note: funded by Novo-Nordisk) of 1,961 individuals, the average weight loss at 68 weeks was 14.9% at the maximum dose of 2.4 mg weekly, equating to 15.3 kg (33.6 lbs) lost compared to 2.6 kg (5.7 lbs) in the placebo group