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Strength training is the proven counter-measure for lean-mass loss in a deficit, and it is the part most patients are never told about

One of the first reports offering real-world data on GLP-1 efficacy found that people using the medicines had lost an average of about 1.4% of their starting body weight after three months, which steadily increased to an average of about 3% weight loss after a full year on the treatment

Cani PD, Hoste S, Guiot Y, Delzenne NM

Side effects at each dose level Side effects are not random

When used in combination with GLP-1, which has glucose-lowering action, it has been shown to be an effective treatment for T2DM and obesity