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People with PCOS often have irregular or absent periods, along with high androgen levels and insulin resistance

Patients should be advised to monitor their blood glucose levels regularly, especially if thirst is accompanied by increased urination, fatigue, or blurred vision

Our studies identify a histone acetylation pathway promoted by KG production that is indispensable for HR proficiency and corresponding resistance to DNA-damaging agents

2 Clinical Effect of SGLT2 Inhibitors The efficacy and safety of SGLT2 inhibitors have been extensively investigated, especially in combination with metformin and/or other glucose-lowering drugs in T2D patients