Rahman S, Archana A, Jan AT, Dutta D, Shankar A, Kim J et al (2019) Molecular insights into the relationship between autoimmune thyroid diseases and breast cancer: a critical perspective on autoimmunity and ER stress
No formal a priori power calculation was performed, as the study was designed as an exploratory observational analysis
A limitation of our study is that we identified only FGF21 as an important cytokine involved in GCGR mAb-induced beta cell regeneration but there might be other cytokines and metabolites that contribute to beta cell regeneration under this condition
Those increases in power output were similar to those previously reported with acute intake of 4.5 g GPLC
The authors reported that the combination was generally tolerated across the tested levels, with adverse events predominantly gastrointestinal and graded mild to moderate, and that the pharmacokinetic profile was consistent with once-weekly administration in the trial design
