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CYP2E1 expression is not reduced (IHC: P=NS), indicating downstream antioxidant protection rather than metabolic source reduction the same mechanistic pattern seen in APAP models

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Although peptides like BPC 157 are not yet FDA-approved, we are seeing promising results in patients seeking relief from a variety of injuries, chronic pain, and inflammation

Thereby, it is possible that this consistent BPC 157 beneficial effect on rat's pathology underlies the sudden onset of encephalopathy with paracetamol overdose as well as paracetamol overdose as the leading cause of acute liver failure in patients (3)