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In APP/PS1 transgenic mice, (D-Ser2)Oxm, a dual GLP-1 and Gcg receptor agonist, notably improves spatial memory and synaptic plasticity, reduces A plaque deposition in the hippocampus, and modulates the PI3K/AKT1/GSK3 signaling pathway [84]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Wolraich M.L., Hagan J.F., Allan C., Chan E., Davison D., Earls M., Evans S.W., Flinn S.K., Froehlich T., Frost J., et al

BEHIND THE HYPE-- GLP-1 MEDS: We spent months digging into the benefits and costs involving GLP-1 medications