doi: 10.1007/s00534-003-0756-8 53 MaJWengLBastianBCChenX
As shown in Table 1 [1,8,12-19] , because of the critical role of this pathway in energy regulation, functional abnormalities caused by mutations in any of its critical genes (e.g., LEP , LEPR , POMC , PCSK1 , MC4R ) can lead to severe early-onset obesity and extreme hyperphagia and are often accompanied by endocrine abnormalities due to deficiencies in related hormones, such as hypogonadism and hypothyroidism [12,20]
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Developed with veterinary input, this specialized formula provides short-term nutritional support when animals are unable or unwilling to consume their regular diet
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