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Results from several animal models have laid the groundwork to move new potential strategies for IGF-I dependent actions on muscle into people (Table 2)

Introduction Have you ever felt like you are doing everything righteating well, staying active, and following your GPs adviceyet the numbers on the scales simply refuse to budge

Your skin barrier is a locked door

CMAJ 2021;193:E4954

Tirzepatide is currently only available on the NHS in England and Wales via specialist weight management services, with a phased roll out to primary care settings in England including GPs